Changing Course solution
by Kegler

The six wordplay only clues solve to soups; as per 25 Across, FROM SOUP TO NUTS, a nut is entered in the diagram instead.

Changing Course solution grid

Across
1O(FF)R + AMP
6REH + ASH (HER rev)
11SINECURE (SURE NICE anag)
12BISQUE (hidden) CASHEW
13LLA + NO (rev)
14LISP (LIPS anag)
16SHORE (HORSE anag)
17BOO + R
18S(HI + PLO)AD
20AER + O (ERA anag)
22NIPA (PAIN anag)
25FROM SOUP TO NUTS
28NEAP (hidden)
30OPrAH
31IN + B + REEDS
33E + MIR (RIM rev)
36COOpER
37D(I + S)H
38CENTS ("SENSE" hom)
39BORS(C)HT (THROBS anag) ALMOND
40TRIANGLE (ALTERING anag)
41OBSESS (hidden)
42F(OND)LED (DON anag)
Down
1OSLO (1st letters)
2CONS + O + M + ME FILBERT
3R + ENO (ONE rev)
4GAZe + PAC + HO (CAP rev) ACORN
5MUL(LION)E + D
6RESHAPE (A SPHERE anag, &lit)
7H + ASPS
8S(HO)OT
9HER + A
10S(WED)IS + H
15MEN + U + DO PISTACHIO
19LENO (ONE-L rev)
20A + F(RICk)AN
21OMER (ROME anag)
23P(UN + D)ITS
24ST(ART) LEo
26H,(BOM)B (rev)
27VERNE (NERVE anag)
29MINE + ST(R)ONE PECAN
32NOLO (LOON anag)
34M + END
35US + ED