A Sound Decision solution
by Kegler

Using VOLUME CONTROL, per 25 Across, ten entries change from one to another of the musical volumes PP, P, F and FF.

A Sound Decision solution grid

Across
1SPART + A (rev)
6BASICS (ABCS IS anag)
12TAPER (PRATE anag)
13GAPE (PAGE anag) {P->FF}
15NOTe
16IRREGULAR (rev hidden)
17PICK + LE {P->F}
19TUFA (hidden)
20L(A + H)ORE
22C(H)AFED (DECAF anag) {F->PP}
24ECHOIC (CHOICE, moving the E)
25VOLUME CONTROL
27B + AND
29SAGE (1st letters)
31REF + U + sTATION {F->P}
34T(A)R
35COR(DONBL)E + U (BLOND anag)
38S + HEEP
40GOO + D
41SNI(P)ER (REINS rev) {P->PP}
42OF COURSE (UFO'S CORE anag) {F->FF}
43WHEY ("WEIGH" hom)
Down
1S + TIPPLE {PP->F}
2PA + RIAH (HAIR rev)
3cREEK
4AGUE (hidden)
5CALI + CO(C)AT
7AFR + O (FAR anag)
8SE(A)T
9INSU(FFEj)RABLE (jEFF rev) {FF->P}
10COPPER (2 defs) {PP->FF}
11STRAD + DLE (DARTS rev; LED anag)
14FA + S(HI)ON
18CHILDPROOF (ORCHID FLOP anag)
21RCMP (rev hidden)
23PETS (rev)
24EU + NU + CH
25VER + TIGO (I GOT anag)
26H(EAR) OF
27BAR + ON
28DONS (2 defs)
30GREECE (hidden)
32TORSO (ROOTS anag)
33PUFFY (2 defs) {FF->PP}
36O(OP)S
37A-I + R
39HEW ("HUGH" hom)